Chain, Ernst Boris

SUBJECT AREA: Medical technology
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b. 19 June 1906 Berlin, Germany
d. 12 August 1979 Ireland
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Anglo-German biochemist and physiologist, co-worker with Florey in the isolation of sufficient supplies of the antibiotic penicillin for clinical use during wartime.
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Chain graduated in Berlin at the Charite Hospital in 1930. A refugee from political persecution, in 1933 he went to the School of Biochemistry in Cambridge, and in 1935 moved to the School of Pathology at Oxford. He became a British subject in 1939. His interests had involved the study of enzymes and the isolation of physiologically active substances from natural sources. In 1938 he drew Florey's attention to Fleming's note of 1929 reporting the bacterial growth inhibiting qualities of Penicillium mould. Using makeshift equipment and with little initial support, they isolated small quantities of penicillin, which they were then able to use clinically with dramatic effect.
Chain had always hoped for adequate resources to develop penicillin and other antibiotics in Britain. This was not forthcoming, however, and in 1948 a research chair and institute was created for him in Rome, at the International Research Centre for Chemical Microbiology. In 1961 he returned to London to the Chair of Biochemistry at Imperial College. There, with the help of a large donation from the Wolfson Foundation, an appropriate building with facilities for the large-scale development and production of biochemical substances was finally made available. His co-equal part in the development of penicillin was recognized by the sharing of the Nobel Prize for Medicine between Florey, Fleming and himself, and he received numerous honours and honorary degrees from a large number of governments and international institutions.
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Principal Honours and Distinctions
Knighted 1944. Nobel Prize for Medicine (jointly with H.W.Florey and A.Fleming) 1945. Fellow of the Royal Society 1949. Ehrlich Prize 1954.
Bibliography
1941, "Penicillin as a chemotherapeutic agent", Lancet (with Florey). 1941, "Further observations on penicillin", Lancet.
1949, Antibiotics, Oxford, (with Florey et al.) MG

Biographical history of technology. - Taylor & Francis e-Librar. . 2005.

Look at other dictionaries:

  • Chain , Ernst Boris — (1906–1979) German–British biochemist Chain, born the son of a chemist in Berlin, Germany, graduated in 1930 from the Friedrich Wilhelm University with a degree in chemistry. He left Germany for England in 1933 and, after two years research at… …   Scientists

  • Chain, Ernst Boris — (1906 79)    Biochemist of German origin. Born in Berlin, he studied at the Pathological Institute of Berlin. Following the rise of the Nazis, he settled in England. In 1945 he received the Nobel Prize for his work on penicillin …   Dictionary of Jewish Biography

  • Ernst Boris Chain — Saltar a navegación, búsqueda Placa homenaje a Ernst Boris Chain en Berlin Moabit, Alemania Ernst Boris Chain nació en 1906 en Berlín (Alemania). En esta ciudad completó sus estudios hasta graduarse en Química, posteriormente su interés por la… …   Wikipedia Español

  • Chain,Sir Ernst Boris — Chain (chān), Sir Ernst Boris. 1906 1979. German born British biochemist. He isolated and purified penicillin; for this achievement he shared a 1945 Nobel Prize with Sir Alexander Fleming, who discovered penicillin in 1928. * * * …   Universalium

  • Ernst Boris Chain — nació en 1906 en Berlín (Alemania). En esta ciudad completó sus estudios hasta graduarse en Química, posteriormente su interés por la incipiente bioquímica lo llevó a trabajar en el Instituto de Patología de Berlín. Más tarde se trasladó a… …   Enciclopedia Universal

  • Ernst Boris Chain — Infobox Scientist name = Sir Ernst Boris Chain box width = image width =150px caption = Ernst Boris Chain birth date = June 19, 1906 birth place = Berlin death date = August 12, 1979 death place = residence = citizenship = British nationality =… …   Wikipedia

  • Ernst Boris Chain — Berliner Gedenktafel in Berlin Moabit (Turmstr. 22, im „Haus der Gesundheit“) Sir Ernst Boris Chain (* 19. Juni 1906 in Berlin; † 12. August 1979 in Castlebar, Irland) war ein deutsch britischer Biochemiker und Bakt …   Deutsch Wikipedia

  • Ernst Boris Chain — Sir Ernst Boris Chain (19 juin 1906 12 août 1979) était un biochimiste allemand, naturalisé britannique qui fut en 1945 colauréat avec Alexander Fleming et Howard Florey du prix Nobel de physiologie ou médecine pour son travail sur la… …   Wikipédia en Français

  • Chain, Sir Ernst Boris — (19 jun. 1906, Berlín, Alemania–12 ago. 1979, Irlanda). Bioquímico británico de origen alemán. Junto con Howard Walter Florey aisló y purificó la penicilina y realizó los primeros ensayos clínicos con el antibiótico. En 1945, Chain, Florey y… …   Enciclopedia Universal

  • Ernst Boris Chain — noun British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906 1979) • Syn: ↑Chain, ↑Sir Ernst Boris Chain • Instance Hypernyms: ↑biochemist …   Useful english dictionary

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